Irène Friedli grew up in Räuchlisberg, Switzerland, and completed her soloist diploma at the Music Academy in Basel. The alto continued her studies in the interpretation class of Dietrich Fischer-Dieskau in Berlin, took part in masterclasses with Brigitte Fassbaender, and received further training with Helen Keller. She won numerous prizes at international song competitions. Since the 1994/95 season, she has been a member of the ensemble at Zurich Opera House. Here she has performed, among others, as the Second and Third Lady (Die Zauberflöte), Mercédès (Carmen), the title role in Ravel’s L’Enfant et les sortilèges, Elsbeth in Schlafes Bruder, Lily in Harley, Annina and Flora (La traviata), Flosshilde (Das Rheingold, Götterdämmerung), Marcellina (Le nozze di Figaro), Emilia (Otello), Lucia (Cavalleria rusticana), Olga in Peter Eötvös’ Three Sisters, Marthe in Gounod’s Faust, Margret (Wozzeck), Lovis in Ronja Räubertochter by Jörn Arnecke, Flower Maiden and Voice from Above (Parsifal), Gertrud/Witch (Hänsel und Gretel), Clotilde (Norma), Mother/Other Mother (Coraline), Fortune Teller (Arabella), and Nurse (Boris Godunov). In the world premiere of the family opera Die Odyssee, she portrayed Eurykleia/Mother, and in Girl with a Pearl Earring, Tanneke. In 2012, she appeared at the Opéra Bastille in Paris. Most recently in Zurich, she has appeared as the Queen of Hearts in Alice in Wonderland, Filipyevna in Eugene Onegin, Tisbe in La Cenerentola, Miss Bentson in Lakmé, Mrs. Waas/Mrs. Grindtooth in Jim Knopf, the Head Chef in Amerika, and Ninetta in I vespri siciliani.